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Effects of Transdermal Testosterone Treatment o... [Endocr Pract. 2014] -...

Comments:No decrease or trend for lower inflammatory markers seen in Testosterone therapy in men > 65.  These men had levels of T Nathan GoodyearTags:Testosterone, inflammation, men, male, hormone,...

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Effects of Long-Term Testosterone Therapy on Patients with “Diabesity”:...

Comments:Six years of Testosterone therapy in men with obesity, low T, and type II Diabetes was found to decrease waist circumference, decrease weight, decrease fasting glucose, decrease in HgbA1c and...

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Risk of Myocardial Infarction in Older Men Receiving Testosterone Therapy

Comments:Testosterone therapy in older men found to provide no increase in MI risk.  In fact, those men with high MI risk, Testosterone provided protection against MI. - Nathan...

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Urinary Hydroxyestrogens and Breast Cancer Risk among Postmenopausal Women: A...

Comments:study finds increases risk of breast cancer in postmenopausal women on HRT with increased 2OH-estrone metabolism.  Confusing? - Nathan GoodyearTags:estrogen metabolism, estrogen, metabolism,...

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http://qjmed.oxfordjournals.org/content/early/2014/08/18/qjmed.hcu173.full.pd...

Comments:Case study published ahead of print--chronic Testosterone use in body building and cardiovascular event in a young man. - Nathan GoodyearTags:Testosterone, therapy, steroids, bodybuilding,...

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Lipoprotein(a), Hormone Replacement Therapy and Risk of Future Cardiovascular...

Comments:study finds HT reduced Lp(a) in women and reduced the Lp(a) association with CVD.  Women not on HT in this study had higher Lp(a) versus those on HT. - Nathan GoodyearTags:hormone,...

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Clinical experience with intravenous administration of ascorbic acid:...

Comments:Great review on the use of IV vitamin C in cancer and to reduce inflammation.  The article does a great job of discussing the mechanism of vitamin C therapy in cancer as well as the proposed...

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Transdermal progesterone cream for vasomotor ... [Obstet Gynecol. 1999] -...

Comments:Transdermal BHRT in the form of Progesterone found to reduce hot flashes by 83%. - Nathan GoodyearTags:progesterone, cream, BHRT, HRT, hormone, therapy, treatment, hot flashes, hot...

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Licorice reduces serum testosterone in heal... [Steroids. 2004 Oct-Nov] -...

Comments:Licorice root extract, also known as glycyrrhizic acid, found to quickly reduce endogenous Testosterone production in women.  The proposed mechanism is via inhibition of 17-hydroxysteroid...

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Retrospective Analysis of Dose Titration an... [Am J Mens Health. 2014] -...

Comments:So this is what passes as science these days.  The study looked at whether pre-therapy Testosterone evaluation was beneficial in men prescribed Testosterone therapy.  What?! - Nathan...

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Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical...

Comments:data on androgen therapy in women is sparse at best.  The conclusion here is suspect: "evidence supports the short-term efficacy and safety of high physiological doses of T" for women with...

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Androgen Therapy Improves Insulin Sensitivity and Decreases Leptin Level in...

Comments:Three month study of men with low T, found that Testosterone therapy improved insulin sensitivity and reduced leptin levels.  The group of men here were described as "healthy, non-obese men"....

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http://www.eurjmedres.com/content/pdf/s40001-014-0056-6.pdf

Comments:Testosterone therapy in obese men with type II Diabetes and low T improved weight,  lipids, HgbA1c, and blood pressure.  There was more improvement with Leptin than with diet/exercise...

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Testosterone deficiency and cardiovascular mortality Morgentaler A, - Asian J...

Comments:Great review by Morgentaler of Testosterone and CVD.  He highlights the significant flaws in the JAMA and the NEJM articles of Testosterone therapy risks.  Morgentaler highlights the...

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Incidence of Prostate Cancer in Hypogonadal Men Receiving Testosterone...

Comments:new study looked at 3 cohorts of Testosterone therapy in men.  The active cohorts found not increased risk of Prostate cancer in men with testosterone therapy at 5 years. - Nathan...

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Incidence of Prostate Cancer in Hypogonadal Men Receiving Testosterone...

Comments:Study of 3 cohorts with a median of 5 years of Testosterone therapy in men with low T, finds no increase risk in prostate cancer. - Nathan GoodyearTags:low t, low Testosterone, hypogonadism,...

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The benefits and risks of testosterone replacement therapy: a review

Comments:review article on risk/benefits of Testosterone therapy in men. - Nathan GoodyearTags:Testosterone, therapy, treatment, low T, low Testosterone, men, male, hormone, hormonesby:Nathan Goodyear

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Testosterone Deficiency, Cardiac Health, and Older Men

Comments:low Testosterone is associated with increased mortality in men and Testosterone therapy in men with low T is associated with a reduction in mortality in men. - Nathan GoodyearHighlights and...

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Testosterone suppresses ventricular remodeling and improves left ventricular...

Comments:Animal model finds that Testosterone improves ventricular remodeling and function following myocardial infarction in male rats.  This similar finding has been found in human studies as well....

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http://iptq.com/uruguay2004.pdf

Comments:study of IPT finds a reduction in progressive disease and tumor size in IPT + MTX compared to MTX alone, and IPT alone. - Nathan GoodyearTags:IPT, Insulin, potentiation, therapy, cancer,...

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